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Watch Intently (3)pentobarbital will reduce the level or result of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Potent or moderate CYP3A4 inducers might improve level of diazepam elimination; for that reason, efficacy of diazepam could be diminished.fentanyl transmucosal and pentobarbita